The Safavid Empire, created by Safi al-Din, was one of the most significant Islamic empires, founded in 1501. The Safavid empire was often known to be the start of the modern Iranian history. The Safavid empire began by having a religious perspective. After 1501, the Safavid Empire obtained military and state features. The kings of Safavid, known as shahs, ruled and formed the second best Islamic Empires. The Safavid Empire was different from Ottoman and Mughal Empire because they were legally Shi’ite, in the case that Shia branch of Islam had different beliefs compared to other Islamic categories. Religious disagreement between the Safavids and a separate branch of Islam known as Sunni led to hostility and problematic issues. The Safavid Empire developed in 1501, lived the shortest among the other two empires, where it suffered in the hands of the invading Afghans, leading to the Safavid Empire destruction and as a result, changing Persian nationalism ever since.Ismail Shah died in 1524. The Shah’s son, Tahmasp I, took over his father’s throne at the age of ten. The new Shah was young and less mature which lead to many struggles between some Qizilbash and individuals who were competing to earn the Shah’s advisory positions; In the case that it could lead to influencing the Safavid Empire. For the first decade of the new Shah’s governing, he made an effort to prevent Uzbeks to dominate Khurasan, and he tried to stop Ottomans from taking over Tabriz. In 1555, an unexpected Ottoman invasion happened to Baghdad, where the Safavid army was struggling in the east fighting back the Uzbeks; Therefore, it led the Ottoman to take over Baghdad and remained in their power for over 100 years. After having continuous attacks between the two empires, they finally signed what is called “The Treaty of Amasya” in 1555, which kept peace among them for the following 25 years.During fifty-two years of Tahmasp’s shahs ruling, the Safavid Empire changed insignificantly apart from the harsh theocratic government formed by Ismail, towards a more extensive secular power. The Shah Tahmasp’s was viewed continuously in political terms, as a ruler, rather than being seen as a moral condition, as the ruler of the Safavid Sufi organization. Under control of Tahmasp, the Safavids further initiated military actions within a new region inside the Caucasus Mountains northland of Persian Kingdom and led numerous attacks approaching the Georgians and the Christian Armenians. Thousands of prisoners were caught and transformed from their nation back to Persia, which changed the racial mix of an imperialism populated mostly by Persians and Turks. Women who were shifted from the Caucasus to the shah’s harem, also known as Kings mention, attempted to get their sons into positions of leadership, and men who were turned to Islam and trained for royal service regularly took up jobs in the court.